General

Jie He

Principal Investigator

Institute of Neuroscience Shanghai

Institutes for Biological Sciences

Chinese Academy of Sciences

Room A0817, The New Life Science Building,

320 Yueyang Road, Shanghai, P.R.China, 200031

Tel: 021-549218961 

Email: jiehe@ion.ac.cn

Research Areas

The proliferation and differentiation mechanism of neuroepithelial cell

The development mechanism of function of visual neural circuit


Education

2000-2005   The Institute of Biophysics, Chinese Academy of  Sciences, Ph.D

1996-2000   Zhejiang UniversityB.S

Experience

   
Work Experience

2005 – 2010  Postdoctoral Fellow, Stowers Institute for Medical Research, USA.

2010 – 2013  Postdoctoral Fellow, The Department of Physiology, Development and  Neuroscience, University of Cambridge, UK 

2013 – Now  Investigator, the Laboratory of Stem Cells and Neurogenesis, The Institute  of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China

Teaching Experience
   

Publications

   
Papers

(1) Bipotent progenitors as embryonic origin of retinal stem cells, Journal of Cell Biology, 2017, Corresponding author.
(2) How Variable Clones Build an Invariable Retina, Neuron, 2012, the first author.
(3) Distinct Signals Conveyed by Pheromone Concentrations to the Mouse Vomeronasal Organ, Journal of Neuroscience, 2010, the first author.
(4) Encoding Gender and Individual Information in the Mouse Vomeronasal Organ, Science, 2008, the first author.

Patents
   

Research Interests

Brain complexity is implemented by astounding diversity of cell types connected in appropriate numbers and combinations. The precise control of neural progenitor/stem cell (NPC/NSC) division and differentiation is a prerequisite for the development and maintenance of circuit integrity, plasticity and regeneration. In the laboratory, our present interest is to develop various genetic and optical tools, by which we hope to gain access to the complete development from single stem (progenitor) cells to their progeny-derived neural circuits in distinct brain regions of zebrafish (Danio rerio), and thereby elucidating the fundamental logics underlying the determination of cell number, neuronal diversity, functional property of neural circuits.

Conferences

   

Collaboration

   

Students

Baijie Xu                                doctoral candidate                                     071006-neuroscience

Mei Wang                              doctoral candidate                                     071006-neuroscience

Shuguang Yu                         doctoral candidate                                     071006-neuroscience

Hui Zhang                              doctoral candidate                                     071006-neuroscience

Yan Li                                    doctoral candidate                                     071006-neuroscience

Lei Du                                    doctoral candidate                                     071006-neuroscience

Huiwen Qin                           master degree candidate                            071006-neuroscience

Mengmeng Jin                       master degree candidate                            071006-neuroscience

 

Honors & Distinctions